These tests can only be ordered by licensed heath care providers

Every GENIE comes with notes by Dr. Ritchie Shoemaker through the Center for Research on Biotoxin Associated Illnesses (CRBAI).

Additionally, a consult appointment can be obtained for further, in depth analysis.

Patients: Please contact your health care provider for help ordering this test.

If you are searching for a CIRS Certified Practitioner click here

Outbound flat rate shipping charges apply only for the continental US. International orders will incur additional shipping charges. Overnight return shipping costs are not included in the price.


GENIE - Gene Expression: Inflammation Explained. This order contains 2 PAXgene tubes to be used to collect your blood sample
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GENIE - Gene Expression: Inflammation Explained. This order contains 2 PAXgene tubes to be used to collect your blood sample
$720.00

Yes, the test is now here. After three years in development and validation, the application of transcriptomics to confirm hypometabolism (see below) is available. Based on the research at Progene DX, for the first time we can use differential gene expression to tell us about abnormalities in gene functioning in illnesses characterized by chronic fatigue. Understanding the gene expression lets us use targeted therapies based on our published, peer-reviewed work.

As you may guess by the name, hypometabolism indicates abnormally low metabolic activity. Finally, we have the definitive test that adds weight to both diagnosis and the sequential monitoring that shows the effects of therapy. Incredible. We don’t have to guess about illnesses without objective biomarkers, like fibromyalgia and Chronic Fatigue Syndrome (CFS). We will define CFS by transcriptomics and not by non-specific symptoms.

And we can show what chronic inflammatory response syndrome (CIRS) truly is in patients harmed by water-damaged buildings (WDB) and Post-Lyme Syndrome.

We can show when healing is complete: the search for the “cure” word is upon us. We can confirm relapse should that tragically occur. We can show progress in the twelve steps of therapy.

Let the newest science train your thinking; conduct your diagnosis and treatment; and guide you to salutary outcomes. This CIRS panel contains 173 reporter genes and 15 housekeeping genes, covering a wide range of areas from mitochondrial ATP synthase to Toll like receptors to caspases and more. These tests can only be ordered in conjunction with licensed heath care providers.

PLEASE NOTE THAT THE PRICE DOES NOT INCLUDE OVERNIGHT RETURN SHIPPING ON DRY ICE. THIS CAN COST $150 FOR DOMESTIC ORDERS.

ORDERS OUTSIDE THE CONTINENTAL US REQUIRE ADDITIONAL SHIPPING AND HANDLING. PLEASE CONTACT US BEFORE ORDERING.

GENIE ORDERS ARE PROCESSED DURING NORMAL BUSINESS HOURS, MONDAY THROUGH FRIDAY, AND SHIPPED WITHIN 48 HRS VIA FED EX GROUND OR USPS PRIORITY MAIL. YOU WILL FIRST BE SENT AN ORDER CONFIRMATION EMAIL UPON PURCHASE, FOLLOWED BY ANOTHER EMAIL WITH TRACKING INFORMATION AS SOON AS THE ORDER HITS THE CARRIERS DELIVERY STREAM. ORDERS TYPICALLY ARRIVE IN 2-3 BUSINESS DAYS ONCE SHIPPED.

After three years in development and validation, the application of transcriptomics to confirm hypometabolism is available. Based on the research at Progene DX, for the first time we can use differential gene expression to tell us about abnormalities in gene functioning in illnesses characterized by chronic fatigue. Understanding the gene expression lets us use targeted therapies based on our published, peer-reviewed work. Read more…


GENIE PAXgene Replacement Tubes
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GENIE PAXgene Replacement Tubes
$50.00

If you lost or damaged your PAXtubes, you can simply replace them with a new set.

If you lost or damaged your GENIE PAXgene tubes, you can simply replace them with a new set.


Rainy Day GENIE: Wholesale GENIE Sample Tube Purchase
$3,375.00

Order the GENIE test in bulk with 5 sets of tubes (enough for five patients) and receive a 10% discount compared to buying one test at a time. You will receive one cooler with your order but you can return the samples for GENIE testing either one at a time, all five together or anything in between. PAXgene tubes can be stored in your clinic at room temperature for at least 6 months. Once a blood sample is drawn into the PAX tube, you can store it in your frost free freezer for two weeks before returning it to the lab. Additional coolers must be supplied by purchaser or purchased separately.

Order the GENIE test in bulk with 5 sets of tubes (enough for five patients) and receive a 10% discount compared to buying one test at a time. You will receive one cooler with your order but you can return the samples for GENIE testing either one at a time, all five together or anything in between. PAXgene tubes can be stored in your clinic at room temperature for at least 6 months. Once a blood sample is drawn into the PAX tube, you can store it in your frost free freezer for two weeks before returning it to the lab. Additional coolers must be supplied by purchaser or purchased separately on our website.


Rainy Day GENIE Sample Submission
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Rainy Day GENIE Sample Submission
$675.00

Use this option if you have samples from the Rainy Day GENIE Wholesale GENIE Sample Tube Purchase you need to return for testing. You will be prompted to add your tube numbers and limited patient information for the samples you are shipping. Please download the Patient History Survey from our website and fill in the tube number with the patient history requested and mail separately to the address listed on the form.

**Use this option only if you purchased Rainy Day GENIE tubes prior to 2021**. You will be prompted to add your tube numbers for the samples you are shipping. Please download the Patient History Survey (linked here) from our website and fill in the tube number along with the patient history requested and mail separately to the address listed on the form.


Progene Services
$50.00

Use this method to pay for services not covered by our regular store items. You can use any quantity of $50 units by adding more of this item to cover costs that are associated with additional services. Please contact us by email or phone before using this function.

Use this method to pay for services not covered by our regular store items. You can use any quantity of $50 units by adding more of this item to cover costs that are associated with additional services. Please contact us by email or phone before using this function.


Replacement Cooler
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Replacement Cooler
$20.00

If you have damaged your cooler and need a replacement to return your samples, you can use this option. Alternatively, a new cooler can be purchased through our distributor at Uline.com, item number S-13391

If you have damaged your cooler and need a replacement to return your samples, you can use this option. Alternatively, a new cooler can be purchased through our distributor at Uline.com, item number S-13391